Dynamic Methylation and Expression of Alternative Promoters for Oestrogen Receptor Alpha in Cell Line Models of Fulvestrant Resistance

Medicine, Endocrinology, Oncology, Life Sciences, Biochemistry,
breast cancer   drug resistance   fulvestrant   methylation   oestrogen receptor   promoter  

Dynamic Changes in Estrogen Receptor Alpha (ERα) Promoter Methylation and Drug Resistance in Breast Cancer Cells Background Breast cancer is one of the most common cancers among women worldwide, with approximately 75% of breast cancer patients expressing estrogen receptor alpha (ERα, gene symbol ESR1). ERα is not only an important prognostic marker...