Role of SDHAF1 in Aging Hematopoietic Stem Cells: Enhancing Metabolic Resilience through Mitochondrial ATP Production

Role of SDHAF1 in Aging Hematopoietic Stem Cells: Enhancing Metabolic Resilience through Mitochondrial ATP Production

Research Background and Objective As individuals age, hematopoietic stem cells (HSCs) progressively accumulate in the bone marrow, exhibiting metabolic resilience under various stress conditions. This metabolic resilience provides an aging advantage for HSCs, enabling them to maintain cell viability even under low metabolic conditions. Although agi...