A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation, and shortened lifespan

Medicine, Geriatrics, Life Sciences, Immunology,
nutrient signaling   mTORC1   parenchymal damage   myeloid inflammation   lifespan  

Research on the Impact of Nutritional Signals on the Lifespan of Mice Background and Motivation In recent years, the intensification of global aging has posed unprecedented challenges to medicine, socio-economics, and philosophy. By 2050, the global population aged 65 and above is expected to grow from 5% at the beginning of the 20th century to 17%...