Optogenetic Inhibition of Glutamatergic Neurons in the Dysgranular Posterior Insular Cortex Modulates Trigeminal Neuropathic Pain in CCI-Ion Rat

Medicine, Basic Medical Sciences, Anesthesiology, Neurology, Neurosurgery,
optogenetics   neuron inhibition   posterior insular cortex   trigeminal neuropathic pain   CCI-Ion  

Optogenetic Inhibition of Insular Cortex Glutamatergic Neurons Regulates Trigeminal Neuropathic Pain Introduction and Background Trigeminal neuropathic pain (TNP) is a severe facial disorder characterized by rapid and intense stabbing pain attacks that spread along the cutaneous segments of the trigeminal nerve. TNP occurs almost twice as frequentl...