An Antibody–Toxin Conjugate Targeting CD47 Linked to the Bacterial Toxin Listeriolysin O for Cancer Immunotherapy

Academic Background Cancer immunotherapy has become a hot topic in cancer research in recent years, with its core goal being to activate the patient’s own immune system to recognize and eliminate cancer cells. However, cancer cells evade immune system attacks through various mechanisms, one of which is the expression of the “don’t eat me” signal mo...

Circulating KLRG1+ Long-Lived Effector Memory T Cells Retain the Flexibility to Become Tissue Resident

Tissue-Resident Capacity of Long-Term Surviving KLRG1+ Effector Memory T Cells Background Memory CD8 T cells play a crucial role in the body’s defense against pathogen reinfection. Memory T cells are a heterogeneous group of cells present in various tissues throughout the body, providing essential surveillance and rapid response functions. Memory T...