Kidney Fibrosis in In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models

Medicine, Basic Medical Sciences, Urology, Nephrology, Life Sciences, Biochemistry, Bioengineering, Immunology,
Kidney fibrosis   Chronic kidney disease   3D humanized models   Disease modeling   Drug development  

Mechanisms and Research Models of Kidney Fibrosis: Progress Toward Physiologically Relevant Humanized Models Research Background and Problem Statement Chronic Kidney Disease (CKD) is a major global public health issue, estimated to affect more than 10% of the population and is one of the leading causes of mortality. Kidney fibrosis, as a key pathol...