Robust Acute Myeloid Leukemia Engraftment in Humanized Scaffolds Using Injectable Biomaterials and Intravenous Xenotransplantation

Medicine, Hematology, Oncology, Life Sciences, Bioengineering,
Acute Myeloid Leukemia   Biomaterials   Xenotransplantation   Bone Marrow Niche   Collagen   Mouse Model   Patient-Derived Xenografts  

Robust Engraftment of Acute Myeloid Leukemia (AML) in Humanized Scaffolds Background Acute myeloid leukemia (AML) is a malignant blood disorder that poses significant challenges in treatment and research. Patient-derived xenograft (PDX) models are crucial tools for studying AML, but existing PDX models are often complex and labor-intensive, limitin...