Inhibitors of Acetohydroxyacid Synthase as Promising Agents Against Non-Tuberculous Mycobacterial Diseases

Chemistry, Medicinal Chemistry, Medicine, Infectious Diseases, Life Sciences, Microbiology,
Acetohydroxyacid Synthase   Non-Tuberculous Mycobacteria   Drug Development   Antimicrobial Activity   Structural Modification   Synergistic Effect   Drug Resistance  

New Hope for the Treatment of Non-Tuberculous Mycobacterial Diseases—Research on Acetohydroxyacid Synthase Inhibitors Academic Background Non-tuberculous mycobacteria (NTM) infections have become an important cause of pulmonary diseases worldwide in recent years, especially among immunocompromised populations. The treatment of NTM infections faces ...

Needs Assessment for the Creation of a Platform Trial Network in Metabolic-Dysfunction Associated Steatohepatitis

Medicine, Hepatobiliary System, Endocrinology,
Metabolic Dysfunction   Steatohepatitis   Clinical Research Network   Platform Trial   Drug Development  

Needs Assessment for Establishing a Platform Trial Network: A Case Study on Metabolic Dysfunction-Associated Steatohepatitis (MASH) Academic Background The public health issue posed by Metabolic Dysfunction-Associated Steatohepatitis (MASH) is becoming increasingly severe. MASH is a condition caused by fat accumulation, inflammation, and cell damag...