Integrative Analysis of Ewing’s Sarcoma Reveals the MIF-CD74 Axis as a Target for Immunotherapy
Discovery of a New Immunotherapy Target for Ewing Sarcoma Background Introduction Ewing sarcoma (Ewing’s sarcoma, EWS) is a common pediatric bone cancer, accounting for approximately 2% of childhood cancers. Despite significant advances in immune checkpoint inhibitors (ICIs) and CAR-T cell therapy in various cancers, their efficacy in Ewing sarcoma...