Comparison of Sonication Patterns and Microbubble Administration Strategies for Focused Ultrasound-Mediated Large-Volume Drug Delivery

Medicine, Medical Laboratory Science, Neurology, Oncology, Life Sciences, Bioengineering, Immunology,
Focused Ultrasound   Microbubbles   Large-Volume Drug Delivery   Blood-Brain Barrier   Immune Checkpoint Inhibitor  

Comparison of Acoustic Patterns and Microbubble Delivery Strategies in Large-Volume Drug Delivery Mediated by Focused Ultrasound for Blood-Brain Barrier Opening Background Diffuse Intrinsic Pontine Glioma (DIPG) is the most common and lethal brainstem tumor in children. Due to the usually intact blood-brain barrier (BBB) in DIPG, drug penetration i...