Targeting Dysregulated Phago-/Auto-Lysosomes in Sertoli Cells to Ameliorate Late-Onset Hypogonadism

Research Background This study focuses on late-onset hypogonadism (LOH), aiming to uncover the mechanisms associated with age-related testicular function deviations, such as LOH, which are not yet fully understood. Utilizing single-cell RNA sequencing technology, the study analyzed the testicles of humans with LOH to identify supporting cells (SCs)...