Pdia3 Defines a Novel Subset of Adipose Macrophages Exacerbating the Development of Obesity and Metabolic Disorders

Pdia3 Defines a Novel Subset of Adipose Macrophages Exacerbating the Development of Obesity and Metabolic Disorders

Novel Subpopulation of Adipose Tissue Macrophages IMAMs and Their Role in Obesity and Metabolic Disorders Background Obesity is an increasingly severe health issue worldwide, often accompanied by a state of chronic low-grade inflammation. This condition is driven by the infiltration and dysfunction of immune cells within adipose tissue and other me...

Genome Sequencing Enables Diagnosis and Treatment of SLC5A6 Neuropathy

Diagnosis and Treatment of SLC5A6-Related Neuropathy: Insights from Genomic Sequencing Academic Background Genomics has always played an important role in the study and treatment of human diseases. The sodium-dependent multivitamin transporter (SMVT) encoded by the SLC5A6 gene is responsible for the uptake of biotin, pantothenic acid, and α-lipoic ...