Nicotinamide Metabolism Face-off Between Macrophages and Fibroblasts Manipulates the Microenvironment in Gastric Cancer

Medicine, Gastroenterology, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
Nicotinamide Metabolism   Macrophages   Fibroblasts   Gastric Cancer   Tumor Microenvironment   Immunotherapy   Extracellular Vesicles  

Macroscopic and Microscopic Mechanisms of Nicotinamide Metabolism Antagonism: Manipulation of the Gastric Cancer Microenvironment Background Introduction Gastric cancer (GC) is a type of cancer characterized by a unique and heterogeneous tumor microenvironment (TME). Despite advances in immune checkpoint blockade (ICB) therapy for gastric cancer, n...