Genetic Risk Stratification and Outcomes Among Treatment-Naive Patients with AML Treated with Venetoclax and Azacitidine

Medicine, Hematology, Oncology,
Acute Myeloid Leukemia   Venetoclax   Azacitidine   Genetic Risk Stratification   Prognostic Model   TP53 Mutation   FLT3-ITD Mutation  

Genetic Risk Stratification and Outcomes Among Treatment-Naive AML Patients Treated with Venetoclax and Azacitidine Academic Background Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy, with prognosis closely related to the genetic characteristics of patients. The European LeukemiaNet (ELN) 2017 and 2022 risk stratifica...

Prognostic Model for High-Grade Neuroendocrine Carcinoma of the Lung Incorporating Genomic Profiling and Poly (ADP-Ribose) Polymerase-1 Expression

Prognostic Model for High-Grade Neuroendocrine Carcinoma of the Lung Incorporating Genomic Profiling and Poly (ADP-Ribose) Polymerase-1 Expression

Medicine, Respiratory System, Oncology, Life Sciences, Biochemistry, Genetics,
High-Grade Neuroendocrine Carcinoma   Genomic Profiling   Poly (ADP-Ribose) Polymerase-1   Prognostic Model   Immunohistochemistry   Tumor Markers   Survival Analysis  

Prognostic Model of Pulmonary High-grade Neuroendocrine Carcinoma: Integrating Genomic Analysis and Poly(ADP-ribose) Polymerase-1 Expression Research Background High-grade neuroendocrine carcinoma (HGNEC) of the lung is a highly aggressive cancer with significant biological complexity. Despite its association with Notch pathway activation and inact...