Exosomes as Biomarkers for Precision Diagnosis of Lung Cancer Academic Background Lung cancer is one of the leading causes of cancer-related deaths worldwide, with early diagnosis and precision treatment of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) remaining significant challenges. Although traditional tissue biopsy is co...

Study on the Four-Way Gene-Smoking Interaction and Survival in Early-Stage Non-Small Cell Lung Cancer Research Background Lung cancer is one of the most prevalent malignancies worldwide and a leading cause of cancer-related mortality. According to global cancer statistics, approximately 2.5 million new cases are diagnosed annually, with 1.8 million...

Academic Background and Problem Statement Idiopathic Pulmonary Fibrosis (IPF) is a progressive interstitial lung disease associated with aging and is an independent risk factor for lung cancer. Epidemiological studies indicate that 3%-22% of IPF patients develop lung cancer during follow-up, with the cumulative incidence increasing over time, makin...

TFF3 Drives Hippo-Dependent EGFR-TKI Resistance in Lung Adenocarcinoma Academic Background Lung adenocarcinoma (LUAD) is one of the most common subtypes of non-small cell lung cancer (NSCLC), with frequent mutations in the epidermal growth factor receptor (EGFR). Since 2013, EGFR tyrosine kinase inhibitors (TKIs) such as gefitinib, erlotinib, and o...

Innovative Advances in Wearable Single-Transducer Echomyography Systems: From Muscle Dynamics Monitoring to Complex Gesture Tracking Academic Background and Research Significance In recent years, wearable electronic devices have garnered significant attention for their enormous potential in health monitoring and human-machine interaction. Electromy...

Pulmonary Embolism (PE) Overview Pulmonary Embolism (PE) is a serious medical emergency with an annual incidence of approximately 60 to 120 cases per 100,000 people in North America and Europe. Most patients are diagnosed with PE in the Emergency Department (ED), and hospitalization is required for the majority of U.S. patients. Anticoagulation is ...

Academic Background and Problem Statement Respiratory diseases impose a significant burden on healthcare systems globally. Although existing pulmonary function tests (such as conventional spirometry) aid in disease diagnosis and monitoring, these methods are relatively insensitive in detecting early-stage diseases and cannot provide information on ...

Low-Dose CT Screening in East Asian Women Who Have Never Smoked: Association Between Family History of Lung Cancer and Ground-Glass Nodule Prevalence and Growth Academic Background Lung cancer is the leading cause of cancer-related mortality worldwide, and smoking is a well-established risk factor for lung cancer. Low-dose CT (LDCT) is an effective...

The Respiratory Microbiome is Linked to the Severity of RSV Infections and the Persistence of Symptoms in Children Academic Background Respiratory Syncytial Virus (RSV) is a leading cause of respiratory infections and hospitalizations in infants. While known risk factors for severe infections include preterm birth, congenital heart disease, and bro...

The Impact of Radioresistant-Related Telomere Genes on Prognosis and Immune Infiltration in Lung Adenocarcinoma Lung adenocarcinoma (LUAD), a common subtype of non-small cell lung cancer (NSCLC), has a high incidence and mortality rate. Despite significant progress in early detection and treatment, the overall survival (OS) rate of LUAD patients re...