MDGA2 Constrains Glutamatergic Inputs Selectively onto CA1 Pyramidal Neurons to Optimize Neural Circuits for Plasticity, Memory, and Social Behavior

Medicine, Neurology, Life Sciences, Cell Biology, Biochemistry, Immunology, Genetics,
MDGA2   CA1 Pyramidal Neurons   Glutamatergic Inputs   Synaptic Plasticity   Memory   Social Behaviors   Autism  

In the field of neuroscience, synaptic organization and plasticity are crucial for cognitive functions such as memory and social behavior. As rare synaptic inhibitory factors, members of the family known as MAM domain-containing glycosylphosphatidylinositol anchor proteins (MDGA) play an important regulatory role in synapse formation by inhibiting ...