Single-cell RNA Sequencing of Peripheral Blood Links Cell-Type-Specific Regulation of Splicing to Autoimmune and Inflammatory Diseases

Medicine, Rheumatology and Immunology, Life Sciences, Immunology, Genetics,
Single-cell RNA sequencing   Splicing regulation   Autoimmune diseases   Inflammatory diseases   Cell-type specificity   Genetic diversity   Asian Immune Diversity Atlas  

Single-cell RNA Sequencing Reveals Cell-type-specific Splicing Regulation in Peripheral Blood Linked to Autoimmune and Inflammatory Diseases Background In recent years, rapid advancements in genomics research have provided deeper insights into the genetic basis of complex traits. However, the functional mechanisms underlying most disease-associated...