Tryptophan 2,3-Dioxygenase-Positive Matrix Fibroblasts Fuel Breast Cancer Lung Metastasis via Kynurenine-Mediated Ferroptosis Resistance of Metastatic Cells and T Cell Dysfunction
Mechanism of Stromal Fibroblasts in Breast Cancer Lung Metastasis Background Introduction Breast cancer is one of the most common cancers among women worldwide, and metastasis is the leading cause of death in breast cancer patients. The lung is one of the most common sites of breast cancer metastasis, yet the mechanisms underlying this process rema...