Synaptic Neoteny of Human Cortical Neurons Requires Species-Specific Balancing of SRGAP2-SYNGAP1

I. Research Background: Neoteny in Human Brain Development and Neurodevelopmental Disorders One of the remarkable features of human brain development is the slow developmental pace of cortical neurons. Compared to other mammals, especially non-human primates, the developmental process of human cortical neurons can last for several years. This neote...

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder Using the PED Algorithm

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder Using the PED Algorithm

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder using the PED Algorithm In the field of neuroinformatics, research on Autism Spectrum Disorder (ASD) predominantly focuses on the bidirectional connectivity between brain regions, with fewer studies addressing higher-order interaction anomalies among brain regions. To explore the comple...

Identification of Autism Spectrum Disorder Using Multiple Functional Connectivity-Based Graph Convolutional Network

The title of this paper is “Identification of Autism Spectrum Disorder Using Multiple Functional Connectivity-based Graph Convolutional Network,” published in the journal “Medical & Biological Engineering & Computing,” volume 62, pages 2133-2144, in 2024. This paper proposes a multiple functional connectivity-based graph convolutional network (mfc-...