The Impairment of Deviance Detection in the Auditory Cortex by DOI Academic Background Psychedelics are a class of psychoactive substances that can significantly alter perception, cognition, and mood. In recent years, psychedelics have shown potential applications in treating conditions such as depression, anxiety, and trauma-related disorders. How...
New Discoveries in Cortical Motor Maps Background Introduction Humans and other primates are capable of performing a wide range of complex body movements, the initiation and control of which rely on multiple cortical and subcortical structures. Among these, the primary motor cortex (M1), located in the precentral gyrus, is the core region for execu...
Research Priorities for Improving Cognitive and Neuropsychological Outcomes in Hydrocephalus Academic Background Hydrocephalus is a neurological disorder affecting approximately 85 per 100,000 individuals worldwide. It is closely associated with motor and cognitive impairments. Although advancements in surgical interventions have significantly impr...
Academic Background Caregivers of patients with Primary Malignant Brain Tumors (PMBT) face significant psychological distress. PMBT is not only an incurable cancer but also accompanied by degenerative neurological conditions, leading caregivers to cope with the gradual loss of the patient’s physical functions and irreversible changes in personality...
D1R-5-HT2AR Uncoupling Alleviates Depressive Behaviors Through HDAC Signaling Research Background Major depressive disorder (MDD) is a globally prevalent and life-threatening mental illness, closely associated with poor physical health. Despite the availability of various treatments, including medications and psychotherapy, many patients exhibit po...
A Mechanism of Brainstem Circuit Enhancing Aversion Response Background and Motivation Aversion response is a natural reaction in humans and animals when faced with threats or unpleasant stimuli, allowing individuals to avoid danger and playing a critical role in adaptation during evolution. However, excessive aversion can lead to a range of emotio...
A Study on the Correlation Between Different Learning Abnormalities and Delusional-like Beliefs of Various Contents Research Background Delusions are a major feature of psychotic disorders (such as schizophrenia, bipolar disorder, depression, and certain neurological and autoimmune diseases). Although delusions clinically manifest as fixed erroneou...
Research Report on Progressive Multidimensional Clinical and Radiological Variations in Patients with Alzheimer’s Disease and Posterior Cortical Atrophy Background Introduction Alzheimer’s Disease (AD) has multiple phenotypes, including the typical amnestic and non-amnestic (atypical) phenotypes. Posterior Cortical Atrophy (PCA) is a prominent atyp...
E-cigarette Cessation SMS Program: A Randomized Clinical Trial Study Targeting Adolescent E-cigarette Users Background In recent years, e-cigarettes have become the most widely used tobacco product among American adolescents. Statistics from 2023 show that over 2.1 million adolescents reported current use of e-cigarettes, including 10% of high scho...
Research Report on FMOD Alleviating Depressive Behavior After Traumatic Brain Injury Traumatic Brain Injury (TBI) is a global health issue with far-reaching impacts, causing not only brain dysfunction but also often leading to mental disorders. One of the most common mental illnesses following TBI is depression, affecting approximately 25-50% of TB...