Poldip2 Mediates Brain Vascular Permeability by Regulating ROS-Mediated ZO-1 Phosphorylation and Localization at the Interendothelial Border

Medicine, Neurology, Life Sciences, Cell Biology,
blood–brain barrier   Poldip2   ZO-1   reactive oxygen species   brain endothelial cells  

POLDIP2 Regulates Cerebral Vascular Permeability by Modulating ROS-Mediated ZO-1 Phosphorylation and Localization Background The blood-brain barrier (BBB) is a critical component of the central nervous system (CNS), composed of brain endothelial cells, astrocytes, pericytes, and neurons. Brain endothelial cells form a continuous physical barrier th...