Adipose-Derived Stem Cells as Carrier of Pro-Apoptotic Oncolytic Myxoma Virus: To Cross the Blood–Brain Barrier and Treat Murine Glioma

Medicine, Medical Laboratory Science, Neurology, Neurosurgery, Oncology, Life Sciences, Cell Biology, Biochemistry, Bioengineering, Immunology,
oncolytic virotherapy   adipose tissue-derived stem cells   glioblastoma   blood–brain barrier   apoptosis   malignant tumors   recurrence  

Crossing the Blood–Brain Barrier: Study on Adipose-Derived Stem Cells as Carriers for Pro-Apoptotic Oncolytic Myxoma Virus in the Treatment of Murine Glioblastoma Background and Objective Glioblastoma (GBM) is among the most invasive and aggressive brain tumors, characterized by high recurrence rates and poor prognosis. Despite multimodal intervent...

Decreased Microvascular Claudin-5 Levels in Cerebral Amyloid Angiopathy Associated with Intracerebral Haemorrhage

Medicine, Neurology, Neurosurgery, Life Sciences, Biochemistry,
blood–brain barrier   cerebral amyloid angiopathy   claudin-5   immunohistochemistry   intracerebral haemorrhage  

Study on Cerebral Amyloid Angiopathy (CAA) and the Level of Tight Junction Protein Claudin-5 in Microvessels Background Cerebral Amyloid Angiopathy (CAA) is a disease caused by the deposition of Amyloid-β (Aβ) in the cerebral blood vessels. Research indicates that approximately 23% of individuals over the age of 55 have moderate to severe CAA. CAA ...