Acetylation of c-Myc at Lysine 148 Protects Neurons After Ischemia

Research Background This study explores the role of the cancer-related transcription factor c-myc in penumbra neurons following ischemic stroke. Although the role of c-myc in cell death and survival has been recognized, research on its post-translational modifications, especially acetylation, in ischemic models remains insufficient. Investigating t...

Acetate Reprogrammes Tumour Metabolism and Promotes PD-L1 Expression and Immune Evasion by Upregulating c-Myc

Acetate Reprogrammes Tumour Metabolism and Promotes PD-L1 Expression and Immune Evasion by Upregulating c-Myc

Acetate Reprograms Tumor Metabolism and Promotes Immune Evasion and PD-L1 Expression by Upregulating c-myc Introduction Reprogramming of tumor metabolism is of great significance in cancer research, and acetate plays a crucial role in this process. In tumor cells, acetate is an important precursor of acetyl-CoA, which is used for energy production,...