Myeloid Beta-Arrestin 2 Depletion Alleviates Metabolic Dysfunction-Associated Steatohepatitis through Metabolic Reprogramming of Macrophages

The Loss of β-arrestin 2 in Hepatic Macrophages Alleviates Metabolic Dysfunction-associated Steatohepatitis — Through Metabolic Reprogramming of Macrophages Background and Motivation Metabolic dysfunction-associated fatty liver disease (MASLD) is a globally prevalent health issue, affecting approximately 25% of the population. This disease includes...

Acetate Reprogrammes Tumour Metabolism and Promotes PD-L1 Expression and Immune Evasion by Upregulating c-Myc

Acetate Reprogrammes Tumour Metabolism and Promotes PD-L1 Expression and Immune Evasion by Upregulating c-Myc

Acetate Reprograms Tumor Metabolism and Promotes Immune Evasion and PD-L1 Expression by Upregulating c-myc Introduction Reprogramming of tumor metabolism is of great significance in cancer research, and acetate plays a crucial role in this process. In tumor cells, acetate is an important precursor of acetyl-CoA, which is used for energy production,...