Cell-Free Tumor DNA Analysis in Advanced or Metastatic Breast Cancer Patients: Mutation Frequencies, Testing Intention, and Clinical Impact

Medicine, Oncology,
cell-free tumor DNA   breast cancer   mutation frequencies   clinical impact   genetic testing  

Academic Background Breast cancer is one of the most common cancers among women worldwide, particularly advanced or metastatic breast cancer, which is challenging to treat and has a poor prognosis. With the development of precision medicine, the role of molecular biomarkers in breast cancer treatment has become increasingly prominent. Circulating t...

Parkinson’s Disease Variant Detection and Disclosure: PD Generation, A North American Study

Medicine, Medical Laboratory Science, Neurology, Life Sciences, Genetics,
Parkinson's disease   genetic testing   genetic counselling   LRRK2   GBA1   clinical trials  

Parkinson’s Disease Variant Detection and Disclosure: Comprehensive Report Background Parkinson’s Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor dysfunction and non-motor symptoms. Research has shown that at least seven genes (LRRK2, GBA1, PRKN, SNCA, PINK1, PARK7, VPS35) are directly related to the occurr...