The Role of Motor Cortex in Striatal Motor Dynamics and Execution of Skilled and Unskilled Actions

Exploring the Crucial Role of the Motor Cortex in Basal Ganglia and Dynamic Motor Control Research Background and Motivation The role of the motor cortex (Motor Cortex, M1) in motor generation and regulation has long been a significant topic in neuroscience. The interaction between M1 and the striatum in selecting and executing goal-directed action...

Disentangling the Heterogeneity of Multiple Sclerosis Through Identification of Independent Neuropathological Dimensions

Research Background Multiple Sclerosis (MS) is a common disease involving lesions in the central nervous system, characterized mainly by demyelination of neuronal axons and neuronal damage. The heterogeneity of the disease is extremely high, meaning that different patients exhibit varying symptoms and pathological mechanisms, which greatly complica...