Alternative mRNA Polyadenylation Regulates Macrophage Hyperactivation via the Autophagy Pathway

NUDT21 Regulates Macrophage Hyperactivation via the Autophagy Pathway Academic Background The inflammatory response is a critical component of the body’s immune defense, facilitating pathogen clearance and tissue repair. However, dysregulation of the inflammatory response can lead to chronic inflammatory diseases such as inflammatory bowel disease ...

Inflammasome Activation Aggravates Choroidal Neovascularization

Report on the Study of Inflammasome Activation Aggravating Choroidal Neovascularization Academic Background Age-related macular degeneration (AMD) is a common retinal disease, particularly among the elderly. AMD is divided into dry and wet types, with wet AMD characterized by choroidal neovascularization (CNV), where abnormal blood vessels grow fro...