Computational Modeling of Receptive Field Construction in Midget Ganglion Cells of Primate Retina

Computational Modeling Study on the Construction of Receptive Fields in Midget Ganglion Cells of Primate Retina Academic Background The midget pathway in the primate retina is the foundation for high spatial resolution and color perception in the visual system. A key feature of this pathway is the center-surround organization of the receptive field...

Control of Movement: Latency and Amplitude of Catch-Up Saccades to Accelerating Targets

The Impact of Retinal Acceleration Error on Catch-Up Saccades Research Background When humans track moving objects, they primarily rely on two types of eye movements: smooth pursuit and saccades. Smooth pursuit depends on visual motion signals, but when tracking errors accumulate, the brain initiates catch-up saccades to realign the gaze with the t...

Chilean Brush-Tailed Mouse (Octodon degus): A Diurnal Precocial Rodent as a New Model to Study Visual Receptive Field Properties of Superior Colliculus Neurons

The Chilean Brush-tailed Mouse (Octodon degus) as a New Model for Studying the Visual System Academic Background The study of the visual system has always been an important topic in the field of neuroscience. Traditionally, scientists have used nocturnal or crepuscular rodents (such as hamsters, rats, and mice) as models to study the development an...

Perisaccadic Perceptual Mislocalization Strength Depends on the Visual Appearance of Saccade Targets

New Findings in Visual Perception and Eye Movement Research Background Introduction In daily life, despite the constant rapid eye movements (known as saccades), we are still able to perceive a stable visual environment. This stability is achieved through the integration of information by the visual system during saccades. However, the mechanisms of...

Co-targeting of Glial Activation and Inflammation by tsRNA-Gln-I-0095 for Treating Retinal Ischemic Pathologies

Study on the Regulatory Mechanism of tsRNA-Gln-i-0095 in Retinal Ischemia-Reperfusion Injury Academic Background Retinal ischemia-reperfusion (I/R) injury is a critical pathological mechanism in various ocular diseases, including glaucoma, central retinal vein occlusion, and retinopathy of prematurity. I/R injury leads to the death of retinal gangl...

Layer-Specific Anatomical and Physiological Features of the Retina’s Neurovascular Unit

Academic Report on the Study of Layer-Specific Anatomical and Physiological Characteristics of the Retinal Neurovascular Unit Background and Problem Statement Retinal processing, similar to all neural computations, is metabolically expensive and involves the dynamic regulation of blood flow, known as neurovascular coupling (NVC). The retina is supp...

Tissue Plasminogen Activator or Perfluoropropane for Submacular Hemorrhage in Age-Related Macular Degeneration: A Factorial Randomized Clinical Trial

Academic Context and Problem Statement Age-related macular degeneration (AMD) is one of the leading causes of vision loss in many high-income countries. Among its forms, neovascular AMD (also known as wet AMD) can be associated with submacular hemorrhage (SMH), a rare but severe condition. If untreated, SMH can lead to significant vision loss. Anti...

Validation of the Online Collaborative Ocular Tuberculosis Study Calculator for Tubercular Uveitis

Academic Background Tubercular Uveitis (TBU) is an ocular condition caused by Mycobacterium tuberculosis infection or immune-mediated inflammation. While tuberculosis (TB) remains a major global public health issue, the diagnosis and treatment of TBU continue to pose significant challenges. TBU presents a wide range of clinical manifestations, with...

Curcuma-Based Nutritional Supplements and Risk of Age-Related Macular Degeneration

Report on Curcuma-Based Nutritional Supplements and the Risk of Age-Related Macular Degeneration Academic Background Age-related macular degeneration (AMD) is one of the leading causes of vision loss among elderly individuals, particularly in developed countries. There are two main types of AMD: non-exudative (dry) and exudative (wet). Dry AMD is c...

Economic Burden of Late-Stage Age-Related Macular Degeneration in Bulgaria, Germany, and the US

Report on the Economic Burden of Late-Stage Age-Related Macular Degeneration in Bulgaria, Germany, and the United States Academic Background Age-related macular degeneration (AMD) is a highly prevalent and debilitating retinal condition, affecting over 200 million people worldwide. Among them, late-stage AMD, which includes neovascular AMD (nAMD) a...