Comprehensive Evaluation of Pipelines for Classification of Psychiatric Disorders Using Multi-Site Resting-State fMRI Datasets

Comprehensive Evaluation of Pipelines for Classification of Psychiatric Disorders Using Multi-Site Resting-State fMRI Datasets

Background Introduction The field of psychiatry has long relied on symptoms and medical interviews for diagnosis, lacking objective biomarkers. Resting-state functional magnetic resonance imaging (rs-fMRI) is widely believed to reveal characteristic patterns of brain structure and function, thereby providing potential classification markers for the...

Gamma Oscillations of Visual Cortex Underlying Emotion and Cognition Deficits Associated with Suicide Attempt in Major Depressive Disorder

Research on Gamma Oscillations Related to Suicidal Behavior in Patients with Depression Introduction Suicide is one of the most severe human behaviors globally, particularly prevalent among patients with Major Depressive Disorder (MDD). Studies have shown that nearly half of those who die by suicide had been diagnosed with MDD. Despite its signific...

Investigation of the Impact of Cross-Frequency Coupling on the Assessment of Depression Severity through the Analysis of Resting State EEG Signals

Background Depression, particularly Major Depressive Disorder (MDD), is a widespread and debilitating psychological disease often described as the “common cold” of mental health. Many people with MDD experience symptoms such as persistent sadness, hopelessness, cognitive impairment, and loss of motivation for daily activities, severely affecting pe...