A Whole Food, Plant-Based Diet Reduces Amino Acid Levels in Patients with Metastatic Breast Cancer

The Impact of a Whole Food, Plant-Based Diet on Amino Acid Levels in Patients with Metastatic Breast Cancer Research Background The growth and survival of cancer cells depend on significant metabolic demands, particularly for amino acids. Tumors meet these demands by acquiring amino acids from the surrounding microenvironment, and dietary amino aci...

The Effect of High Protein Dosing in Critically Ill Patients: An Exploratory, Secondary Bayesian Analyses of the EFFORT Protein Trial

The Effect of High Protein Dosing in Critically Ill Patients: An Exploratory, Secondary Bayesian Analysis of the EFFORT Protein Trial Academic Background In the field of critical care medicine, nutritional support is a crucial component of treating critically ill patients. Protein, as a fundamental requirement for cellular function and survival, pl...

Utilizing a Yeast Genetic Model to Validate the Pathogenicity of ACTA2 Variants Associated with Aortic Aneurysms

Pathological Study of a New ACTA2 Mutation Causing Aortic Aneurysm: Validation Using a Yeast Model Research Background Thoracic aortic aneurysm and dissection (TAAD) is a potentially fatal vascular disease with mechanisms that are still not fully understood. The ACTA2 gene encodes α-smooth muscle actin, a key component of the vascular smooth muscle...