Seeding Activity of Human Superoxide Dismutase 1 Aggregates in Familial and Sporadic Amyotrophic Lateral Sclerosis Postmortem Neural Tissues by Real-Time Quaking-Induced Conversion
Detection of Seeding Activity of Human Superoxide Dismutase 1 Aggregates in Postmortem Neural Tissues of Familial and Sporadic Amyotrophic Lateral Sclerosis Patients Background Introduction Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressing neurodegenerative disease with an average survival time of 2 to 5 years after diagnosis. Major symp...