Aging-induced tRNAglu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization

Aging-induced trnaGlu-derived fragments disrupt glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization Academic Background Mitochondrial cristae are inward protrusions of the inner mitochondrial membrane that undergo significant morphological changes during aging. However, the molecular mechanisms leading to th...