Aging-induced tRNAglu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization

Aging-induced trnaGlu-derived fragments disrupt glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization Academic Background Mitochondrial cristae are inward protrusions of the inner mitochondrial membrane that undergo significant morphological changes during aging. However, the molecular mechanisms leading to th...

Interaction Between the Gut Microbiota and Colonic Enteroendocrine Cells Regulates Host Metabolism

Interaction Between the Gut Microbiota and Colonic Enteroendocrine Cells Regulates Host Metabolism

Interaction Between Gut Microbiota and Colonic Enteroendocrine Cells Regulates Host Metabolism Research Background Obesity is a major health issue in the 21st century and a significant factor contributing to various adverse health consequences such as diabetes, fatty liver disease, and cardiovascular diseases. Therefore, exploring the biological me...