Integrating Single-Nucleus RNA Sequencing and Spatial Transcriptomics to Elucidate a Specialized Subpopulation of Astrocytes, Microglia, and Vascular Cells in a Mouse Model of Lipopolysaccharide-Induced Sepsis-Associated Encephalopathy
Study on Mouse Sepsis-Associated Encephalopathy Based on Single Cell and Spatial Transcriptomics Background Organ dysfunction leading to death in sepsis is related to an imbalance in the host’s response to infection, and it has a high global mortality rate. Recent studies have shown that sepsis can cause brain dysfunction, known as sepsis-associate...