Study on Reducing Toxicity of CAR-T Cell Therapy for Solid Tumors Academic Background Chimeric antigen receptor T-cell (CAR-T) therapy has made significant progress in treating hematologic malignancies, but its application in solid tumors faces major challenges. Solid tumors often lack tumor-specific antigens (TSAs), and CAR-T cells may attack norm...

Miltefosine Reinvigorates Exhausted T Cells by Targeting Their Bioenergetic State Academic Background T cell exhaustion is a significant challenge in immunotherapy, particularly in cancer treatment. It typically occurs when T cells are chronically exposed to antigen stimulation, leading to a gradual loss of function, characterized by reduced effect...