Silencing of STEAP3 Suppresses Cervical Cancer Cell Proliferation and Migration via JAK/STAT3 Signaling Pathway

Medicine, Oncology,
STEAP3   cervical cancer   JAK/STAT3 signaling pathway   cell proliferation   cell migration   DNA methylation   iron metabolism  

The Role and Mechanism of STEAP3 in Cervical Cancer Background Cervical cancer (CC) is the fourth most common cancer among women globally, with approximately 600,000 new cases and 300,000 deaths annually. Although the five-year survival rate for early-stage cervical cancer patients exceeds 85% through treatments such as surgery, radiotherapy, and c...

Assembly of Recombinant Proteins into β-Sheet Fibrillating Peptide-Driven Supramolecular Hydrogels for Enhanced Diabetic Wound Healing

Chemistry, Medicinal Chemistry, Medicine, Life Sciences, Biochemistry, Bioengineering,
supramolecular hydrogels   diabetic wound healing   β-sheet fibrillating peptides   recombinant proteins   cell migration   epidermal regeneration   biofunctional materials  

Supramolecular Hydrogels Driven by β-Sheet Fibrillating Peptides for Enhanced Diabetic Wound Healing Academic Background Diabetic wound healing is a global health issue. Due to microvascular complications and immune dysfunction caused by hyperglycemia, the wound healing process in diabetic patients is often severely hindered. Traditional treatments...

Functional Correlation between Myeloid Cells and Membrane Abundance

Medicine, Rheumatology and Immunology, Life Sciences, Cell Biology, Immunology, Biophysics,
myeloid cells   membrane abundance   phagocytosis   G protein β4 subunit   cell migration   biophysical regulation  

In the past few decades, with the rapid development of science and technology, human understanding of the immune system has continuously deepened. Among all immune cells, professional phagocytes (such as neutrophils and macrophages) play a crucial role in clearing apoptotic cells, cell debris, and invading pathogens. These cells uptake and engulf f...