Miltefosine Reinvigorates Exhausted T Cells by Targeting Their Bioenergetic State Academic Background T cell exhaustion is a significant challenge in immunotherapy, particularly in cancer treatment. It typically occurs when T cells are chronically exposed to antigen stimulation, leading to a gradual loss of function, characterized by reduced effect...

Tumor Immunology Research: The Exhausted State of CD8+ T Cells in Tumors In recent years, immunotherapy has achieved significant progress in the field of tumor treatment. However, tracking the behavior of lymphocytes following antigen signals remains challenging. This study aims to address this issue by developing Antigen Receptor Signaling Reporte...