Academic Background Duchenne Muscular Dystrophy (DMD) is a genetic muscular disorder and the most common type of muscular dystrophy in Japan. DMD is caused by a mutation in the dystrophin gene on the X chromosome, leading to the absence or defect of the dystrophin protein in muscle fibers. This results in a cascade of events, including increased mu...

Academic Background Duchenne Muscular Dystrophy (DMD) is a severe X-linked recessive disorder characterized by progressive muscle wasting, leading to premature mortality. The cause of DMD is mutations in the gene encoding dystrophin, a protein that, along with other proteins at the muscle cell membrane, forms the Dystrophin-Glycoprotein Complex (DG...