Academic Background and Problem Statement Retinopathy of Prematurity (ROP) is a common retinal neurovascular disorder in premature infants, primarily occurring in those whose retinal vascular development is incomplete. Due to exposure to a relatively hyperoxic environment after birth, especially with supplemental oxygen therapy, hyperoxia suppresse...

Academic Background Duchenne Muscular Dystrophy (DMD) is a genetic muscular disorder and the most common type of muscular dystrophy in Japan. DMD is caused by a mutation in the dystrophin gene on the X chromosome, leading to the absence or defect of the dystrophin protein in muscle fibers. This results in a cascade of events, including increased mu...

Nynrin Protects Hematopoietic Stem Cell Function by Inhibiting Mitochondrial Permeability Transition Pore Opening Background and Research Motivation Hematopoietic stem cells (HSCs) are core cells that maintain the function of the hematopoietic system, showing unique adaptability to stress environments such as radiation damage. However, while conven...