Spatial Transcriptome Profiling Identifies DTX3L and BST2 as Key Biomarkers in Esophageal Squamous Cell Carcinoma Tumorigenesis

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology, Genetics,
Esophageal squamous cell carcinoma   Tumorigenesis   Spatial transcriptome   Single-cell transcriptome   Tumor-associated macrophage   Polarization   Spatial biomarker   Functional studies  

Digital Spatial Transcriptomics Highlights DTX3L and BST2 as Crucial Biomarkers in Esophageal Squamous Cell Carcinoma Tumorigenesis Background and Research Question Esophageal cancer (EC) remains a globally prevalent malignant disease with high incidence and mortality rates. Esophageal squamous cell carcinoma (ESCC), the most common histological su...