Human Cortical Neurogenesis is Altered via Glucocorticoid-Mediated Regulation of ZBTB16 Expression

Human Cortical Neurogenesis is Altered via Glucocorticoid-Mediated Regulation of ZBTB16 Expression

Glucocorticoids Alter Human Cortical Neurogenesis by Regulating ZBTB16 Expression Background Introduction During pregnancy, glucocorticoids (GCs) are crucial steroid hormones for the development of the central nervous system (CNS). GCs regulate the development of fetal organs, particularly the lungs and brain. However, when GC levels exceed the phy...

Molecular Targets of Glucocorticoids that Elucidate Their Therapeutic Efficacy in Aggressive Lymphomas

Analysis of Molecular Targets of Glucocorticoids in the Treatment of Aggressive Lymphomas Academic Background Glucocorticoids (GCs) have been used for over 70 years in the treatment of hematological malignancies, but their mechanisms of action remain unclear. Clinically, glucocorticoids show significant efficacy in treating lymphomas but not in mye...