Major Breakthrough in Research for Autoimmune Neuroinflammation Treatment Background Introduction Steroid resistance is a significant challenge in the treatment of many inflammatory diseases, particularly autoimmune neuroinflammation. In these diseases, TH17 cells (T helper 17 cells) are widely regarded as key contributors to steroid resistance; ho...

TH17 Endogenous IL-1β–STAT5 Axis Drives Steroid Resistance in Autoimmune Neuroinflammation Academic Background Steroid resistance is a major challenge in managing various inflammatory diseases, including autoimmune neuroinflammation. T helper 17 (TH17) cells are widely believed to be associated with steroid resistance. However, the specific mechani...