Intermittent Hypoxia Exacerbates Anxiety in High-fat Diet-Induced Diabetic Mice by Inhibiting TREM2-Regulated IFNAR1 Signaling

Medicine, Respiratory System, Psychiatry, Endocrinology, Neurology,
Type 2 Diabetes Mellitus   Obstructive Sleep Apnea   Anxiety   Microglia   TREM2   IFNAR1   Cognition  

Over the past few decades, the incidence of type 2 diabetes mellitus (T2DM) has been on the rise, becoming a global public health issue. T2DM not only affects patients’ metabolic levels but also has profound impacts on cognitive function and mental health. Studies have shown that patients with T2DM exhibit brain structural abnormalities, a decline ...

Effects of a Single Night of Continuous Positive Airway Pressure on Spontaneous Brain Activity in Severe Obstructive Sleep Apnea

Medicine, Respiratory System, Neurology, Clinical Psychology, Medical Imaging,
Obstructive Sleep Apnea   Continuous Positive Airway Pressure   Spontaneous Brain Activity   Fractional Amplitude of Low-Frequency Fluctuation   Regional Homogeneity  

The Effect of Single-Night Continuous Positive Airway Pressure on Spontaneous Brain Activity in Patients with Severe Obstructive Sleep Apnea Research Background Obstructive sleep apnea (OSA) is a common chronic sleep-related breathing disorder characterized by partial or complete closure of the airway during sleep. This condition leads to repeated ...