Targeted Delivery of Napabucasin with Radiotherapy Improves Outcomes in Diffuse Midline Glioma

Targeted Delivery of Napabucasin with Radiotherapy in Diffuse Midline Glioma Background Introduction Diffuse Midline Glioma (DMG) is the most aggressive primary brain tumor in children, with a median survival typically less than one year. Although radiation therapy (RT) is the current standard treatment, it only provides transient symptom relief an...

Neuroprotective Effects of Sinomenine on Experimental Autoimmune Encephalomyelitis via Anti-inflammatory and Nrf2-dependent Anti-oxidative Stress Activity

Research Background on Multiple Sclerosis and Central Nervous System Inflammation Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS), often accompanied by chronic inflammation, leading to oligodendrocyte loss, activation of brain-resident immune cells, blood-brain barrier disruption, extensive demyelin...