Phosphorylation of Piezo1 at a Single Residue, Serine-1612, Regulates Its Mechanosensitivity and In Vivo Mechanotransduction Function

Medicine, Basic Medical Sciences, Neurology, Life Sciences, Cell Biology, Biochemistry, Genetics, Biophysics,
Piezo1   Serine-1612   Phosphorylation   Mechanotransduction   Endothelial Cells   Blood Pressure Regulation  

This article is a biomedical research paper authored by scholars such as Zhang Tingxin, Bi Cheng, and Li Yiran, published on November 6, 2024, in the journal “Neuron.” The research was led by a team from the Tsinghua University-Peking University Center for Life Sciences, exploring the regulatory mechanism of phosphorylation modification of the mech...

Mechanosensitive Ion Channels Piezo1 and Piezo2 in Vivo Mediate Motor Response During Transcranial Focused Ultrasound Stimulation of Rodent Cerebral Motor Cortex

Mechanosensitive Ion Channels Piezo1 and Piezo2 in Vivo Mediate Motor Response During Transcranial Focused Ultrasound Stimulation of Rodent Cerebral Motor Cortex

Medicine, Basic Medical Sciences, Neurology, Medical Imaging, Life Sciences, Biophysics,
transcranial focused ultrasound   neuromodulation   cerebral motor cortex   Piezo1   Piezo2  

Piezo1 and Piezo2 Mechanosensitive Ion Channels Regulate the Response of Rodents to Transcranial Focused Ultrasound Stimulation of the Motor Cortex Academic Background Transcranial Focused Ultrasound (TFUS) neuromodulation is a non-invasive, deep brain stimulation technique that shows great potential in the study of neural circuits and the treatmen...