Report: Revealing White Matter Changes Associated with Tau in Early Alzheimer’s Disease through Fixel-based Analysis Research Background Alzheimer’s Disease (AD) is generally thought to primarily affect the grey matter (GM), but more and more evidence shows that the white matter (WM) also experiences abnormalities. Current research largely relies o...

Background Introduction Diffusion Tensor Magnetic Resonance Imaging (DTI) is a widely used neuroimaging technique for imaging the microstructure of brain tissues and white matter tracts. However, noise in Diffusion-Weighted Images (DWI) can reduce the accuracy of microstructural parameters derived from DTI data and also necessitate longer acquisiti...

DeepDTI: High-Fidelity Six-Direction Diffusion Tensor Imaging Using Deep Learning Research Background and Motivation Diffusion Tensor Imaging (DTI) boasts unparalleled advantages in mapping the microstructure and structural connectivity of live human brain tissue. However, traditional DTI techniques require extensive angular sampling, leading to pr...