Stochastic Modeling of Single-Cell Gene Expression Adaptation Reveals Non-Genomic Contribution to Evolution of Tumor Subclones

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology, Genetics,
stochastic modeling   gene expression adaptation   tumor subclones   Wnt signaling   immunotherapy   non-genomic contribution   cellular evolution  

Stochastic Modeling of Single-Cell Gene Expression Adaptation Reveals Non-Genomic Contribution to Tumor Subclone Evolution Academic Background Cancer is a complex disease whose progression is driven by the evolution of cells that are selected through adaptive advantages for growth. Traditionally, cancer evolution research has focused primarily on g...