The Ventral Subiculum Promotes Wakefulness Through Multiple Pathways in Male Mice Background The ventral subiculum (vsub) is a major output region of the hippocampus, playing a crucial role in motivation, stress integration, and anxiety-like behavior, all of which depend on a high state of wakefulness. However, the role of vsub in wakefulness and i...

Sodium Leak Channel in Glutamatergic Neurons of the Lateral Parabrachial Nucleus Helps Maintain Respiratory Rate Under Sevoflurane Anesthesia Background Respiration is a core function for maintaining life activities. General anesthetics and/or opioids often suppress respiratory function. However, the respiratory suppression caused by the intravenou...

Thalamic Reuniens Nucleus Glutamatergic Neurons Mediated Colorectal Visceral Pain in Mice through 5-HT2B Receptors Background Irritable Bowel Syndrome (IBS) is a common functional bowel disorder characterized by abdominal pain and visceral hypersensitivity. Reducing visceral hypersensitivity is crucial for effectively alleviating abdominal pain in ...