Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Project to Bed Nucleus of the Stria Terminalis to Regulate Wakefulness and Positive Emotional States Background The nucleus accumbens (NAc) plays a crucial role in regulating motivation, reward, and many behaviors that depend on high levels of arousal. However, research on the neural mechani...

The Ventral Subiculum Promotes Wakefulness Through Multiple Pathways in Male Mice Background The ventral subiculum (vsub) is a major output region of the hippocampus, playing a crucial role in motivation, stress integration, and anxiety-like behavior, all of which depend on a high state of wakefulness. However, the role of vsub in wakefulness and i...