Modeling Ocular Surface Ion and Water Transport by Generation of Lipid- and Mucin-Producing Human Meibomian Gland and Conjunctival Epithelial Cells

Modeling of Ion and Water Transport on the Human Ocular Surface Background Introduction The ocular surface plays a crucial role in human physiology and diseases, especially the stability and composition of the tear film, which directly impact ocular surface health. The tear film consists of three layers: an outer lipid layer (secreted by the meibom...

Revisiting Distinct Nerve Excitability Patterns in Patients with Amyotrophic Lateral Sclerosis

“Revisiting Distinct Nerve Excitability Patterns in Patients with Amyotrophic Lateral Sclerosis” Academic Background Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive loss of central and peripheral motor neurons. Although the disease is clinically and genetically heterogeneous, axonal hy...